1. 主要研究方向: 聚焦岭南特色药用植物,综合应用现代色谱、光谱技术,辅以现代活性筛选技术,分离、鉴定和发现活性新成分,运用现代药理研究手段,围绕“南药”重点开展中药抗肿瘤疾病及作用机理研究,揭示中药药效物质基础,为新药研究提供活性先导化合物。 2. 承担项目 广东省普通高校青年创新人才项目1项(2021KQNCX049),主持,在研 岭南师范学院博士启动项目1项(ZL1903),主持,在研 岭南师范学院粤西特色生物医药工程技术研究中心开放课题1项(2022-K04),主持,在研 3. 主要成果 (1) Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Si-Yu Zhao; Xiao-Ping Song; Chang-Ri Han; New aromatic lactone derivatives with inhibitory activities on nitric oxide production from Homalium stenophyllum, Phytochemistry Letters, 2018, 25: 95-98. (2) Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Chang-Ri Han; Xiao-Ping Song; Biologically active oligostilbenes from the stems of Vatica mangachapoi and chemotaxonomic significance, Natural Product Research, 2019, 33: 2300-2307. (3) Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Si-Yu Zhao; Chang-Ri Han; Xiao-Ping Song; Bioactive Phenolic and Isocoumarin Glycosides from the Stems of Homalium paniculiflorum, Molecules, 2018, 23: 472-472. (4) Shou-Yuan Wu; Yan-Hui Fu; Qi Zhou; Meng Bai; Guang-Ying Chen; Chang-Ri Han; Xiao-Ping Song; A new dihydrochalcone glycoside from the stems of Homalium stenophyllum, Natural Product Research, 2018, 32: 953-958. (5) Shou-Yuan Wu; Yan-Hui Fu; Guang-Ying Chen; Xiao-Bao Li; Qi Zhou; Chang-Ri Han; Xiao-Ping Song; Xiang-Jiao Du; Min-Li Xie; Guo-Gui Yao; Cytotoxic xanthene derivatives from Homalium paniculiflorum, Phytochemistry Letters, 2015, 11: 236-239. (6) Qi Zhou; Shou-Yuan Wu; Chun-Xiao Jiang; Ying-Peng Tong; Ting Zhao; Bin Zhang; Xu-Hua Nong; Ze-Xin Jin; Jin-Feng Hu; A new coumarin derivative from the stems of the endangered plant Ulmus elongate, Natural Product Research, 2021, 35(21): 3562-3568. (7) Qi Zhou; Chun-Xiao Jiang; Shou-Yuan Wu*; Zi-Ming Chen; Li-Ping Huang; A new indole alkaloid from the stems of Glycosmis puberula var. craibii, Natural Product Research, 2022, 36(1): 379-384. (8) Shou-Yuan Wu; Meng-Bai; Qi-Zhou; Xu-Hua Nong; Guang-Ying Chen; Si-Yu Zhao; Chang-Ri Han; Xiao-Ping Song; Phenolic glycosides from the stems of Homalium stenophyllum, Chinese Journal of Natural Medicines, 2021, 19(3): 225-230. (9) Shou-Yuan Wu; Zi-Ming Chen; Zhong-Liu Zhou; Li-Ping Huang; Guo-Ling Huang; Qi Zhou; Unusual oximes with anti-inflammatory activities from Glycosmis craibii, Phytochemistry Letters, 2021, 44: 202-205. (10) Shou-Yuan Wu; Zi-Ming Chen; Guang-Ying Chen; Xiao-Ping Song; Chang-Ri Han; Two New Phenolic Glycosides from Homalium stenophyllum, Chemistry of Natural Compounds, 2021, 57(4): 663-666. (11) Shou-Yuan Wu; Zi-Ming Chen; Guo-Ling Huang; Zhou-Liu Zhou; LI-Png Huang; Xiao-Chun Jiang; Qi Zhou; A New Tyramine Derivative from the Branches and Leaves of Glycosmis craibii, Chemistry of Natural Compounds, 2021, 57(5): 894-898. (12) 吴寿远; 周戚; 陈子明; 黄国玲 ; 毛山小橘枝叶中生物碱类成分的研究, 热带亚热带植物学报, 2022, 30(3): 441-445. (13) Shou-Yuan Wu; Guo-Ling Huang; Zhong-Liu Zhou; Zi-Ming Chen; Chemical Constituents from the Solid Culture of the Edible Mushroom Flammulina velutipes, Chemistry of Natural Compounds, 2022, 58(5): 981-983. (14) Shou-Yuan Wu; Zi-Ming Chen; Zhong-Liu Zhou; Guo-Ling Huang; Qi Zhou; Yan-Jie Xi ; New cinnamic acid derivatives with potential neuroprotective activities from the stems of Melicope ptelefolia, Phytochemistry Letters, 2023, 53: 161-165. (15) Shou-Yuan Wu; Zi-Ming Chen; Qi Zhou; Guo-Ling Huang; Zhong-Liu Zhou; Meng Bai ; Structurally diverse sulphur-containing amides from Glycosmis craibii with their potential antiproliferative activities, Fitoterapia, 2023, 165: 105418. |